This summer for the 50th anniversary of the film, Warner Bros. is releasing a 70mm print of 2001: A Space Odyssey made from the original camera negative. Christopher Nolan, who oversaw the process, explains that this release will be as close to what Kubrick intended as possible:
For the first time since the original release, this 70mm print was struck from new printing elements made from the original camera negative. This is a true photochemical film recreation. There are no digital tricks, remastered effects, or revisionist edits. This is the unrestored film — that recreates the cinematic event that audiences experienced fifty years ago.
Here's a trailer for the new print:
On YouTube, Krishna Ramesh Kumar compared some of the shots in this trailer with those from the 2007 Blu-ray version of the film. Some of the scenes look pretty different in tone: